POLYVALAN competitive edge is its unique chemical approach allowing significant gain of effectiveness, time and/or precision for protein structure determination that allows an optimal use of the existing large equipments.
Crystal Structure of LDH-like malate dehydrogenase co-crystallized with 10 mM Tb-Xo4 Crystallophore displays
-dual substrate recognition,
-and an alternative oligomeric organization.
The crystals were grown in 2 days.
Thanks to Polyvalan Tb-Xo4's high phasing power, the protein crystal structure determination process is greatly facilitated, thus saving samples and time, and can be extended to serial crystallography approaches.